Actor Christina Applegate reveals she was misdiagnosed with multiple sclerosis
The Married … with Children actor says the news is ‘unnerving’ and ‘really confusing’

TL;DR
- Christina Applegate announced she was misdiagnosed with multiple sclerosis (MS) after believing she had the disease since 2021.
- Applegate shared her emotional reaction on her podcast MeSsy, expressing feelings of confusion and distress, and stating she still experiences many of the same physical symptoms.
- She felt she had let down the MS community she had become an advocate for, losing a 'reason' for her daily struggles.
- Applegate plans to work with her doctors to understand why she received the misdiagnosis.
- Both Applegate and her podcast co-host Jamie-Lynn Sigler, who has MS, discussed the prevalence of misdiagnoses, particularly concerning MS.
- A Swiss-led study published in the Multiple Sclerosis Journal indicated high proportions of MS misdiagnosis and underdiagnosis.