Actor Christina Applegate reveals she was misdiagnosed with multiple sclerosis

The Married … with Children actor says the news is ‘unnerving’ and ‘really confusing’

Actor Christina Applegate reveals she was misdiagnosed with multiple sclerosis

TL;DR

  • Christina Applegate announced she was misdiagnosed with multiple sclerosis (MS) after believing she had the disease since 2021.
  • Applegate shared her emotional reaction on her podcast MeSsy, expressing feelings of confusion and distress, and stating she still experiences many of the same physical symptoms.
  • She felt she had let down the MS community she had become an advocate for, losing a 'reason' for her daily struggles.
  • Applegate plans to work with her doctors to understand why she received the misdiagnosis.
  • Both Applegate and her podcast co-host Jamie-Lynn Sigler, who has MS, discussed the prevalence of misdiagnoses, particularly concerning MS.
  • A Swiss-led study published in the Multiple Sclerosis Journal indicated high proportions of MS misdiagnosis and underdiagnosis.