Christina Applegate reveals she was misdiagnosed with multiple sclerosis: "Not happy at all"
Updated on: October 20, 2026 / 7:32 PM EDT / CBS News
TL;DR
- Christina Applegate announced that she was misdiagnosed with multiple sclerosis (MS) more than five years after her initial diagnosis.
- The misdiagnosis came to light after her doctor questioned her infusion treatment and observed her B cell count.
- Applegate expressed unhappiness with the misdiagnosis, stating that her symptoms have continued and even worsened.
- She described the misdiagnosis as unnerving and confusing, and is now undergoing a new investigation with her doctors to identify the cause of her health issues.
- Multiple sclerosis is a disease where the immune system attacks the central nervous system, and misdiagnoses are considered fairly common due to the lack of a single definitive test.