Sweetener used in chewing gum and jam linked to strokes and heart attacks

High blood levels of xylitol associated with higher risk of major cardiovascular events, in largest study of its kind

Sweetener used in chewing gum and jam linked to strokes and heart attacks

TL;DR

  • High blood levels of xylitol, a common artificial sweetener, are linked to an increased risk of strokes, heart attacks, and death.
  • In the largest study of its kind, researchers found that individuals with the highest xylitol blood levels were 57% more likely to experience major adverse cardiovascular events within six years.
  • A dose-dependent relationship was observed, indicating that higher xylitol blood levels correlate with a higher rate of cardiovascular events.
  • The association between xylitol and cardiovascular events was independent of baseline characteristics such as age, sex, body mass index, hypertension, diabetes, and lipid levels.
  • Previous research suggested xylitol can enhance platelet clot formation, adding to concerns about its cardiovascular safety.
  • Experts emphasize that while this observational study shows an association, further research is required to prove direct causation, and it does not endorse increased sugar intake as an alternative.