From ‘Ozempic breath’ to hair loss: sorting the science from the hype about weight loss jabs

Do you gain weight once you stop using them? Do they make your face saggy? Can they improve your mental health? Experts explain whether 13 common beliefs about GLP-1s are true or false

From ‘Ozempic breath’ to hair loss: sorting the science from the hype about weight loss jabs

TL;DR

  • GLP-1 medications suppress appetite by mimicking natural hormones but do not eliminate hunger.
  • Common side effects include nausea, constipation, and diarrhea, which often improve over time.
  • These drugs can lead to nutrient deficiencies if the diet quality is poor.
  • Weight lost while taking GLP-1s is often regained upon stopping the medication.
  • Muscle loss can occur with weight loss, necessitating protein-rich foods and resistance training.
  • Not everyone responds to GLP-1s, with 5-20% classified as non-responders.
  • GLP-1s were developed for type 2 diabetes and obesity, not purely aesthetic reasons.
  • There is limited evidence for mental health benefits, but some promising results for addiction.
  • Anecdotal evidence suggests 'Ozempic breath' and sulfurous burps may occur due to fermentation.
  • Hair loss (telogen effluvium) can be a temporary side effect due to stress on the body.
  • Facial sagging can occur due to loss of fat support, making skin appear wrinkled.
  • Potential benefits beyond weight loss, such as reduced risk of certain cancers and cardiovascular events, are being researched.